People

Stevan Springer

I study phenotypic effects of genetic changes to infer mechanisms of adaptive evolution in natural populations

Organismal behavior in molecular detail

I use experimental and computational tools to study molecular systems:

how their changes influence behavioral phenotypes and what their evolution can tell us about adaptation

Curriculum Vitae

2016

18	Distinguishing spandrels and phenotypic targets of molecular evolution Springer SA, Manhart M, Morozov AV Biodiversification from Genotype to Phenotype 2016 (in press)
17	Des variations génétiques nouvelles préservent l'esprit des personnes âgées Springer SA, Gagneux P Médicine et Science 2016 (in press)
16	Maintenance of postreproductive cognitive capacity by inclusive fitness Springer SA, Schwartz F, Altheide T, Varki NM, Varki A, Gagneux P (2016) PNAS 2016 doi: 1073/pnas. 1601419113
15	Human-specific derived alleles of CD33 and other genes protect against postreproductive cognitive decline Schwarz F, Springer SA, Altheide T, Varki NM, Gagneux P, Varki A PNAS 2016 113:74-79
14	Glycomics: revealing the dynamic ecology and evolution of sugar molecules Springer SA, Gagneux P Journal of Protemics 2016 135:90-100

2015

Evolutionary analysis and classification of OATs, OCTs, OCTNs, and SLC22 transporters
Zhu C, Nigam KB, Date RC, Springer SA, Saier MH, Wu W, Nigam SK
PLoS One 2015 10(11): e0140569

2014

12

Parallel evolution of a self-signal: humans and new world monkeys independently lost the cell surface sugar Neu5Gc
Springer SA, Diaz SL, Gagneux P
Immunogenetics 2014 66:671-674

2013

11	Duplicate abalone egg coat proteins bind sperm lysine similarly, but evolve oppositely, consistent with molecular mimicry at fertilization Asgaard JE, Springer SA, Soelberg SD, Swanson WJ PLoS Genetics 2013 9(2): e1003287
10	Glycan evolution in response to collaboration, conflict, and constraint Springer SA, Gagneux P JBC 2013 28:6904-6911

2011

09	Sexual selection by female immunity against paternal antigens can fix loss of function alleles Ghaderi D, Springer SA,MA F*, Cohen M, Secrest P, Taylor R, Varki A, Gagneux P PNAS 2001 108:17443-17448
08	Beyond the phenotypic gambit: molecular behavioral ecology and the evolution of genetic architecture Springer SA, Crespi BJ, Swanson WJ Molecular Ecology 2011 20:2240-2257

2009

Coevolution of interacting fertilization proteins
Clark NL, Gasper J, Sekino M, Springer SA, Aquadro CF, Swanson WJ
PLoS Genetics 2009 5(7): e1000570

2008

06	Oyster sperm binding is a combinatorial fucose lectin with remarkable intra-species diversity Springer SA, Moy GW, Friend DS, Swanson WJ, Vacquier VD Int j Dev Biol 2008 52:759-768
05	Extraordinary intraspecific polymorphism in oyster sperm binding Moy GW, Springer SA, Adams SL, Swanson WJ, Vacquier VD PNAS 2008 105:1993-1998

2007

04	Adaptive gamete-recognition divergence in a hybridizing Mytilus population Evolution 2007 61:722-783
03	Environment-specific heterozygote deficiency and developmental instability in hybrid Mytilus Mar Biol Res 2007 3:182-187

2004

Implications of the Copernican Principle for my Master thesis
Springer SA
Ann Improb Res 2004 10.4:20-21

2003

01

Social slime molds meet their match
Crespi B and Springer SA
Science 2003 299:56-57