News

Data Released From Adolescent Brain Development Study Led by UC San Diego

UC San Diego News Center - Kim McDonald - February 13, 2018

The first datasets from the largest long-term study of brain development and child health in the United Statesa project headed by a team of scientists at UC San Diegowere released to researchers around the world today by the National Institutes of Health.

To date, more than 7,500 youth and their families have been recruited for the Adolescent Brain Cognitive Development or ABCD study. In addition, approximately 30 terabytes of data—about three times the size of the Library of Congress collection—have been obtained from the first 4,500 participants. ...

Contributors to this study included CTIPM Director Dr. Anders Dale, Informatics Director Hauke Bartsch, and Imaging Technology Co-Director Joshua M. Kuperman.


 

Data Released From Adolescent Brain Development Study Led by UC San DiegoHuge study of teen brains could reveal roots of mental illness, impacts of drug abuse

American Association for the Advancement of Science – Science Magazine – January 3, 2018

Chya* (pronounced SHY-a), who is not quite 10 years old, recently spent an unusual day at the University of Maryland School of Medicine in Baltimore. Part of the time she was in a "cool" brain scanner while playing video games designed to test her memory and other brain-related skills. At other points, she answered lots of questions about her life and health on an iPad.

A slender Baltimore third grader who likes drawing, hip hop, and playing with her pet Chihuahua, Chya is one of more than 6800 children now enrolled in an unprecedented examination of teenage brain development. The Adolescent Brain Cognitive Development Study—or ABCD Study—will complete its 2-year enrollment period in September, and this month will release a trove of data from 4500 early participants into a freely accessible, anonymized database. Ultimately, the study aims to follow 10,000 children for a decade as they grow from 9- and 10-year-olds into young adults. ... 

Contributors to this study included CTIPM Director Dr. Anders Dale, Informatics Director Hauke Bartsch, and Imaging Technology Co-Director Joshua M. Kuperman.


 

Genetics Overlap Found Between Alzheimer’s Disease and Cardiovascular Risk Factors

Inflammation and high blood lipids may play role in dementia risk, but also offer therapeutic targets
UCSD Press Release – April 16, 2015

An international team of scientists, led by researchers at University of California, San Diego School of Medicine, have found genetic overlap between Alzheimer’s disease (AD) and two significant cardiovascular disease risk factors: high levels of inflammatory C-reactive protein (CRP) and plasma lipids or fats. The findings, based upon genome-wide association studies involving hundreds of thousands of individuals, suggest the two cardiovascular phenotypes play a role in AD risk – and perhaps offer a new avenue for potentially delaying disease progression. The findings are published in current online issue of Circulation. …

CTIPM Director Dr. Anders Dale was a senior author of this study.
Dr. James Brewer, co-director of Neurology & Neuro-Imaging at CTIPM, and Dr. David Karow, director of Oncologic Imaging at CTIPM, were co-authors of the study.


Family income, parental education related to brain structure in children and adolescents

Children’s Hospital Los Angeles – March 30, 2015

Characterizing associations between socioeconomic factors and children's brain development, a team including investigators from nine universities across the country reports correlative links between family income and brain structure. Relationships between the brain and family income were strongest in the lowest end of the economic range - suggesting that interventional policies aimed at these children may have the largest societal impact. The study, led by researchers at The Saban Research Institute of Children's Hospital Los Angeles and Columbia University Medical Center, will be published in the early online edition of the journal Nature Neuroscience on March 30. …

Contributors to this study included CTIPM Director Dr. Anders Dale, Informatics Director Hauke Bartsch, and Imaging Technology Co-Director Joshua M. Kuperman.


Neuroimaging Advances for Alzheimer's Disease - On Our Mind

The Brain Channel, UCSD TV – Feb. 16, 2015

What insights into Alzheimer's disease can cutting edge imaging techniques reveal? James Brewer, MD, PhD joins William Mobley, MD, PhD to discuss how this unique window into the brain can be used to study the progression of the disease as well as help test new therapies.

Dr. James Brewer is co-director of Neurology & Neuro-Imaging at CTIPM


Novel Imaging Technique Improves Prostate Cancer Detection

More accurate diagnoses could mean less invasive interventions, more surveillance
UCSD Press Release – January 6, 2015

In 2014, prostate cancer was the leading cause of newly diagnosed cancers in men and the second leading cause of cancer death in men. Writing in the January 6, 2015 issue of the journal Prostate Cancer and Prostatic Disease, a team of scientists and physicians from the University of California, San Diego School of Medicine, with counterparts at University of California, Los Angeles, describe a novel imaging technique that measurably improves upon current prostate imaging – and may have significant implications for how patients with prostate cancer are ultimately treated. …

Nathan White, co-director of Information Technology at CTIPM, was the study’s co-author and co-inventor of the RSI-MRI technique. Dr. David Karow, Director of Oncologic Imaging at CTIPM, was the study’s corresponding author. Other co-authors included CTIPM Director Dr. Anders Dale, Imaging Technology Co-Director Joshua M. Kuperman, and Informatics Director Hauke Bartsch.


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