Shigella Antibiotic Resistance
In the United States, most
Shigella is already resistant to the antibiotics ampicillin and trimethoprim/sulfamethoxazole. The first choice of treatment today is ciprofloxacin, but resistance is already increasing globally. Until recently, resistance to ciproflacin in the US was only 2% of
Shigella infections, but resistance was found in 90% of samples tested from recent clusters. Ciprofloxacin-resistant
Shigella sickened 243 people in 32 US states between 2014-2015. CDC researchers discovered that the illness was repeatedly introduced as sick travelers returned, infecting others in a series of outbreaks around the US.