Publications

4Randomized placebo-controlled trial of losartan for pediatric NAFLD. 

Vos MB, Van Natta ML, Blondet NM, Dasarathy S, Fishbein M, Hertel P, Jain AK, Karpen SJ, Lavine JE, Mohammad S, Miriel LA, Molleston JP, Mouzaki M, Sanyal A, Sharkey EP, Schwimmer JB, Tonascia J, Wilson LA, Xanthakos SA; NASH Clinical Research Network. Hepatology. 2022 Aug;76(2):429-444. doi: 10.1002/hep.32403. Epub 2022 Feb 28.PMID: 35133671 Clinical Trial. 

5 Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease. 

Cohen CC, Li KW, Alazraki AL, Beysen C, Carrier CA, Cleeton RL, Dandan M, Figueroa J, Knight-Scott J, Knott CJ, Newton KP, Nyangau EM, Sirlin CB, Ugalde-Nicalo PA, Welsh JA, Hellerstein MK, Schwimmer JB, Vos MB. J Clin Invest. 2021 Dec 15;131(24):e150996. doi: 10.1172/JCI150996.PMID: 34907907 Free PMC article. Clinical Trial. 

6 The Prevalence of Elevated Alanine Aminotransferase Levels Meeting Clinical Action Thresholds in Children with Obesity in Primary Care Practice. 

Wu SJ, Darbinian JA, Schwimmer JB, Yu EL, Ramalingam ND, Greenspan LC, Lo JC.J Pediatr. 2022 Jan;240:280-283. doi: 10.1016/j.jpeds.2021.09.033. Epub 2021 Sep 23.PMID: 34562443 

7 Recent advances in the epidemiology of nonalcoholic fatty liver disease in children. 

Shapiro WL, Noon SL, Schwimmer JB. Pediatr Obes. 2021 Nov;16(11):e12849. doi: 10.1111/ijpo.12849. Epub 2021 Sep 9.PMID: 34498413 Review. 

8 Pediatric nonalcoholic fatty liver disease and the microbiome: Mechanisms contributing to pathogenesis and progression. 

Salzman NH, Schwimmer JB. Curr Opin Endocr Metab Res. 2021 Aug;19:22-29. doi: 10.1016/j.coemr.2021.05.003. Epub 2021 May 17.PMID: 34222711 Free PMC article. 

9 Magnetic resonance elastography biomarkers for detection of histologic alterations in nonalcoholic fatty liver disease in the absence of fibrosis. 

Qu Y, Middleton MS, Loomba R, Glaser KJ, Chen J, Hooker JC, Wolfson T, Covarrubias Y, Valasek MA, Fowler KJ, Zhang YN, Sy E, Gamst AC, Wang K, Mamidipalli A, Schwimmer JB, Song B, Reeder SB, Yin M, Ehman RL, Sirlin CB. Eur Radiol. 2021 Nov;31(11):8408-8419. doi: 10.1007/s00330-021-07988-6. Epub 2021 Apr 26.PMID: 33899143 

10 Epidemiology of Pediatric Nonalcoholic Fatty Liver Disease. 

Yu EL, Schwimmer JB. Clin Liver Dis (Hoboken). 2021 Apr 13;17(3):196-199. doi: 10.1002/cld.1027. eCollection 2021 Mar.PMID: 33868665 Free PMC article. Review. No abstract available. 

11 Repeatability and accuracy of various region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. Hong CW, Cui JY, Batakis D, Xu Y, Wolfson T, Gamst AC, Schlein AN, Negrete LM, Middleton MS, Hamilton G, Loomba R, Schwimmer JB, Fowler KJ, Sirlin CB. Abdom Radiol (NY). 2021 Jul;46(7):3105-3116. doi: 10.1007/s00261-021-02965-5. Epub 2021 Feb 20.PMID: 33609166 Free PMC article. 

12 Hepatic Steatosis is Negatively Associated with Bone Mineral Density in Children. 

Chun LF, Yu EL, Sawh MC, Bross C, Nichols J, Polgreen L, Knott C, Schlein A, Sirlin CB, Middleton MS, Kado DM, Schwimmer JB. J Pediatr. 2021 Jun; 233:105-111.e3. doi: 10.1016/j.jpeds.2021.01.064. Epub 2021 Feb 3.PMID: 33545191 Free PMC article. 

13 Dairy Fat Intake, Plasma Pentadecanoic Acid, and Plasma Iso-heptadecanoic Acid Are Inversely Associated With Liver Fat in Children. 

Sawh MC, Wallace M, Shapiro E, Goyal NP, Newton KP, Yu EL, Bross C, Durelle J, Knott C, Gangoiti JA, Barshop BA, Gengatharan JM, Meurs N, Schlein A, Middleton MS, Sirlin CB, Metallo CM, Schwimmer JB.J Pediatr Gastroenterol Nutr. 2021 Apr 1;72 (4):e90-e96. doi: 10.1097/MPG.0000000000003040.PMID: 33399331 Free PMC article. 

14 Incidence of Depression and Anxiety in a Cohort of Adolescents With Nonalcoholic Fatty Liver Disease. 

Noon SL, D'Annibale DA, Schwimmer MH, Shiels J, Arin J, Durelle J, Newton KP, Goyal NP, Schwimmer JB.J Pediatr Gastroenterol Nutr. 2021 Apr 1;72(4):579-583. doi: 10.1097/MPG.0000000000003024.PMID: 33346572 Free PMC article. 

15 Incidence of Nonalcoholic Fatty Liver Disease in Children: 2009-2018. 

Sahota AK, Shapiro WL, Newton KP, Kim ST, Chung J, Schwimmer JB. Pediatrics. 2020 Dec; 146(6):e20200771. doi: 10.1542/peds.2020-0771.PMID: 33214329 Free PMC article. 

16 Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice. 

Xanthakos SA, Lavine JE, Yates KP, Schwimmer JB, Molleston JP, Rosenthal P, Murray KF, Vos MB, Jain AK, Scheimann AO, Miloh T, Fishbein M, Behling CA, Brunt EM, Sanyal AJ, Tonascia J; NASH Clinical Research Network. Gastroenterology. 2020 Nov; 159(5):1731-1751.e10. doi: 10.1053/j.gastro.2020.07.034. Epub 2020 Jul 23.PMID: 32712103 Free PMC article. 

17 Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis. 

Newton KP, Lavine JE, Wilson L, Behling C, Vos MB, Molleston JP, Rosenthal P, Miloh T, Fishbein MH, Jain AK, Murray KF, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Hepatology. 2021 Mar;73(3):937-951. doi: 10.1002/hep.31317. Epub 2020 Nov 30.PMID: 32416645 Free PMC article. Clinical Trial. 

18 Prospective comparison of longitudinal change in hepatic proton density fat fraction (PDFF) estimated by magnitude-based MRI (MRI-M) and complex-based MRI (MRI-C). 

Mamidipalli A, Fowler KJ, Hamilton G, Wolfson T, Covarrubias Y, Tran C, Fazeli S, Wiens CN, McMillan A, Artz NS, Funk LM, Campos GM, Greenberg JA, Gamst A, Middleton MS, Schwimmer JB, Reeder SB, Sirlin CB. Eur Radiol. 2020 Sep; 30(9):5120-5129. doi: 10.1007/s00330-020-06858-x. Epub 2020 Apr 21.PMID: 32318847 Free PMC article. 

19 Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH. 

Loomba R, Neuschwander-Tetri BA, Sanyal A, Chalasani N, Diehl AM, Terrault N, Kowdley K, Dasarathy S, Kleiner D, Behling C, Lavine J, Van Natta M, Middleton M, Tonascia J, Sirlin C; NASH Clinical Research Network. Hepatology. 2020 Oct;72(4):1219-1229. doi: 10.1002/hep.31121. Epub 2020 Oct 9.PMID: 31965579 Free PMC article. Clinical Trial. 

20 Accuracy of common proton density fat fraction thresholds for magnitude- and complex-based chemical shift-encoded MRI for assessing hepatic steatosis in patients with obesity. 

Cunha GM, Thai TT, Hamilton G, Covarrubias Y, Schlein A, Middleton MS, Wiens CN, McMillan A, Agni R, Funk LM, Campos GM, Horgan S, Jacobson G, Wolfson T, Gamst A, Schwimmer JB, Reeder SB, Sirlin CB.Abdom Radiol (NY). 2020 Mar;45(3):661-671. doi: 10.1007/s00261-019-02350-3.PMID: 31781899 Free PMC article. 

21 Evaluation of Quantitative Imaging Biomarkers for Early-phase Clinical Trials of Steatohepatitis in Adolescents. 

Goyal NP, Sawh MC, Ugalde-Nicalo P, Angeles JE, Proudfoot JA, Newton KP, Middleton MS, Sirlin CB, Schwimmer JB.J Pediatr Gastroenterol Nutr. 2020 Jan;70(1):99-105. doi: 10.1097/MPG.0000000000002535.PMID: 31633654 Free PMC article. 

22 Factors to Consider in Development of Drugs for Pediatric Nonalcoholic Fatty Liver Disease. 

Vos MB, Dimick-Santos L, Mehta R, Omokaro SO, Taminiau J, Schabel E, Kleiner DE, Szitanyi P, Socha P, Schwimmer JB, Noviello S, Silberg DG, Torstenson R, Miller V, Lavine JE; Liver Forum Pediatric Working Group.Gastroenterology. 2019 Dec;157(6):1448-1456.e1. doi: 10.1053/j.gastro.2019.08.048. Epub 2019 Sep 12.PMID: 31520612 Free PMC article. No abstract available. 

23 Normal range for MR elastography measured liver stiffness in children without liver disease. 

Sawh MC, Newton KP, Goyal NP, Angeles JE, Harlow K, Bross C, Schlein AN, Hooker JC, Sy EZ, Glaser KJ, Yin M, Ehman RL, Sirlin CB, Schwimmer JB.J Magn Reson Imaging. 2020 Mar;51(3):919-927. doi: 10.1002/jmri.26905. Epub 2019 Aug 27.PMID: 31452280 Free PMC article. 

24 Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease. 

Schwimmer JB, Johnson JS, Angeles JE, Behling C, Belt PH, Borecki I, Bross C, Durelle J, Goyal NP, Hamilton G, Holtz ML, Lavine JE, Mitreva M, Newton KP, Pan A, Simpson PM, Sirlin CB, Sodergren E, Tyagi R, Yates KP, Weinstock GM, Salzman NH.Gastroenterology. 2019 Oct;157(4):1109-1122. doi: 10.1053/j.gastro.2019.06.028. Epub 2019 Jun 27.PMID: 31255652 Free PMC article. 

25 Low Free Sugar Diet in Adolescents With Nonalcoholic Fatty Liver Disease-Reply. 

Schwimmer JB, Ugalde-Nicalo P, Vos MB.JAMA. 2019 Jun 25;321(24):2469. doi: 10.1001/jama.2019.5153.PMID: 31237636 No abstract available. 

26 Measurement of spleen fat on MRI-proton density fat fraction arises from reconstruction of noise. 

Hong CW, Hamilton G, Hooker C, Park CC, Tran CA, Henderson WC, Hooker JC, Fazeli Dehkordy S, Schwimmer JB, Reeder SB, Sirlin CB.Abdom Radiol (NY). 2019 Oct;44(10):3295-3303. doi: 10.1007/s00261-019-02079-z.PMID: 31172210 Free PMC article. 

27 Relationship between resolution of non-alcoholic steatohepatitis and changes in lipoprotein sub-fractions: a post-hoc analysis of the PIVENS trial. 

Corey KE, Wilson LA, Altinbas A, Yates KP, Kleiner DE, Chung RT, Krauss RM, Chalasani N; NASH Clinical Research Network.Aliment Pharmacol Ther. 2019 May;49(9):1205-1213. doi: 10.1111/apt.15216. Epub 2019 Mar 10.PMID: 30854694 Free PMC article. Clinical Trial. 

28 Pilot study on longitudinal change in pancreatic proton density fat fraction during a weight-loss surgery program in adults with obesity. 

Covarrubias Y, Fowler KJ, Mamidipalli A, Hamilton G, Wolfson T, Leinhard OD, Jacobsen G, Horgan S, Schwimmer JB, Reeder SB, Sirlin CB.J Magn Reson Imaging. 2019 Oct;50(4):1092-1102. doi: 10.1002/jmri.26671. Epub 2019 Jan 30.PMID: 30701611 Free PMC article. 

29 Effect of a Low Free Sugar Diet vs Usual Diet on Nonalcoholic Fatty Liver Disease in Adolescent Boys: A Randomized Clinical Trial. 

Schwimmer JB, Ugalde-Nicalo P, Welsh JA, Angeles JE, Cordero M, Harlow KE, Alazraki A, Durelle J, Knight-Scott J, Newton KP, Cleeton R, Knott C, Konomi J, Middleton MS, Travers C, Sirlin CB, Hernandez A, Sekkarie A, McCracken C, Vos MB.JAMA. 2019 Jan 22;321(3):256-265. doi: 10.1001/jama.2018.20579.PMID: 30667502 Free PMC article. Clinical Trial. 

30 Clinical Practice Approach to Nonalcoholic Fatty Liver Disease by Pediatric Gastroenterologists in the United States. 

Shapiro WL, Yu EL, Arin JC, Murray KF, Ali S, Desai NK, Xanthakos SA, Lin HC, Alkhouri N, Abdou R, Abrams SH, Butler MW, Faasse SA, Gillis LA, Hadley TA, Jain AK, Kavan M, Kordy K, Lee P, Panganiban J, Pohl JF, Potter C, Rudolph B, Sundaram SS, Joshi S, Proudfoot JA, Goyal NP, Harlow KE, Newton KP, Schwimmer JB.J Pediatr Gastroenterol Nutr. 2019 Feb;68(2):182-189. doi: 10.1097/MPG.0000000000002194.PMID: 30640271 Free PMC article.  

31 Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis. 

Banini BA, Cazanave SC, Yates KP, Asgharpour A, Vincent R, Mirshahi F, Le P, Contos MJ, Tonascia J, Chalasani NP, Kowdley KV, McCullough AJ, Behling CA, Schwimmer JB, Lavine JE, Sanyal AJ; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).J Clin Gastroenterol. 2019 Nov/Dec;53(10):750-758. doi: 10.1097/MCG.0000000000001142.PMID: 30586008 Free PMC article. Clinical Trial. 

32 Monitoring Fatty Liver Disease with MRI Following Bariatric Surgery: A Prospective, Dual-Center Study. 

Pooler BD, Wiens CN, McMillan A, Artz NS, Schlein A, Covarrubias Y, Hooker J, Schwimmer JB, Funk LM, Campos GM, Greenberg JA, Jacobsen G, Horgan S, Wolfson T, Gamst AC, Sirlin CB, Reeder SB.Radiology. 2019 Mar;290(3):682-690. doi: 10.1148/radiol.2018181134. Epub 2018 Dec 18.PMID: 30561273 Free PMC article. 

33 Prevalence of Nonalcoholic Fatty Liver Disease in Children with Obesity. 

Yu EL, Golshan S, Harlow KE, Angeles JE, Durelle J, Goyal NP, Newton KP, Sawh MC, Hooker J, Sy EZ, Middleton MS, Sirlin CB, Schwimmer JB.J Pediatr. 2019 Apr;207:64-70. doi: 10.1016/j.jpeds.2018.11.021. Epub 2018 Dec 14.PMID: 30559024 Free PMC article. 

34 Non-alcoholic fatty liver disease in pediatric type 2 diabetes: Metabolic and histologic characteristics in 38 subjects. 

Newfield RS, Graves CL, Newbury RO, Schwimmer JB, Proudfoot JA, Say DS, Feldstein AE.Pediatr Diabetes. 2019 Feb;20(1):41-47. doi: 10.1111/pedi.12798. Epub 2018 Dec 9.PMID: 30467936 

35 Breastfeeding and NAFLD from the maternal side of the mother-infant dyad. 

Nobili V, Schwimmer JB, Vajro P.J Hepatol. 2019 Jan;70(1):13-14. doi: 10.1016/j.jhep.2018.10.030. Epub 2018 Nov 7.PMID: 30414736 No abstract available. 

36 Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease. 

Elbel EE, Lavine JE, Downes M, Van Natta M, Yu R, Schwimmer JB, Behling C, Brunt EM, Tonascia J, Evans R.Hepatol Commun. 2018 Sep 27;2(10):1213-1226. doi: 10.1002/hep4.1232. eCollection 2018 Oct.PMID: 30288476 Free PMC article. 

37 A Bibliometric Analysis of Clinical and Translational Research in Pediatric Gastroenterology From 1970 to 2017. 

Schwimmer MH, Sawh MC, Heskett KM, Goyal NP, Newton KP, Schwimmer JB.J Pediatr Gastroenterol Nutr. 2018 Nov;67(5):564-569. doi: 10.1097/MPG.0000000000002056.PMID: 29901549 Free PMC article. 

38 Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease. 

Harlow KE, Africa JA, Wells A, Belt PH, Behling CA, Jain AK, Molleston JP, Newton KP, Rosenthal P, Vos MB, Xanthakos SA, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).J Pediatr. 2018 Jul;198:76-83.e2. doi: 10.1016/j.jpeds.2018.02.038. Epub 2018 Apr 13.PMID: 29661561 Free PMC article. 

39 Genetic Variants Associated With Obesity and Insulin Resistance in Hispanic Boys With Nonalcoholic Fatty Liver Disease. 

Rausch JC, Lavine JE, Chalasani N, Guo X, Kwon S, Schwimmer JB, Molleston JP, Loomba R, Brunt EM, Chen YI, Goodarzi MO, Taylor KD, Yates KP, Rotter JI; NASH Clinical Research Network.J Pediatr Gastroenterol Nutr. 2018 May;66(5):789-796. doi: 10.1097/MPG.0000000000001926.PMID: 29470286 Free PMC article. 

40 How bariatric surgery affects liver volume and fat density in NAFLD patients. 

Luo RB, Suzuki T, Hooker JC, Covarrubias Y, Schlein A, Liu S, Schwimmer JB, Reeder SB, Funk LM, Greenberg JA, Campos GM, Sandler BJ, Horgan S, Sirlin CB, Jacobsen GR.Surg Endosc. 2018 Apr;32(4):1675-1682. doi: 10.1007/s00464-017-5846-9. Epub 2017 Dec 7.PMID: 29218660 Free PMC article. 

41 Sources of systematic error in proton density fat fraction (PDFF) quantification in the liver evaluated from magnitude images with different numbers of echoes. 

Bydder M, Hamilton G, de Rochefort L, Desai A, Heba ER, Loomba R, Schwimmer JB, Szeverenyi NM, Sirlin CB.NMR Biomed. 2018 Jan;31(1):10.1002/nbm.3843. doi: 10.1002/nbm.3843. Epub 2017 Nov 12.PMID: 29130539 Free PMC article. 

42 Association Between Cytokines and Liver Histology in Children with Nonalcoholic Fatty Liver Disease. 

Perito ER, Ajmera V, Bass NM, Rosenthal P, Lavine JE, Schwimmer JB, Yates KP, Diehl AM, Molleston JP, Murray KF, Scheimann A, Gill R, Glidden D, Aouizerat B.Hepatol Commun. 2017 Sep;1(7):609-622. doi: 10.1002/hep4.1068. Epub 2017 Jul 17.PMID: 29130075 Free PMC article. 

43 The Genetics of Pediatric Nonalcoholic Fatty Liver Disease. 

Goyal NP, Schwimmer JB.Clin Liver Dis. 2018 Feb;22(1):59-71. doi: 10.1016/j.cld.2017.08.002. Epub 2017 Oct 5.PMID: 29128061 Free PMC article. Review. 

44 Response to the Letters Regarding the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition NAFLD Guidelines. 

Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA.J Pediatr Gastroenterol Nutr. 2017 Nov;65(5):e115-e116. doi: 10.1097/MPG.0000000000001731.PMID: 29059122 No abstract available. 

45 Diagnostic accuracy of magnetic resonance imaging hepatic proton density fat fraction in pediatric nonalcoholic fatty liver disease. 

Middleton MS, Van Natta ML, Heba ER, Alazraki A, Trout AT, Masand P, Brunt EM, Kleiner DE, Doo E, Tonascia J, Lavine JE, Shen W, Hamilton G, Schwimmer JB, Sirlin CB; NASH Clinical Research Network.Hepatology. 2018 Mar;67(3):858-872. doi: 10.1002/hep.29596. Epub 2018 Jan 26.PMID: 29028128 Free PMC article. Clinical Trial. 

46 Cross-sectional correlation between hepatic R2* and proton density fat fraction (PDFF) in children with hepatic steatosis. 

Mamidipalli A, Hamilton G, Manning P, Hong CW, Park CC, Wolfson T, Hooker J, Heba E, Schlein A, Gamst A, Durelle J, Paiz M, Middleton MS, Schwimmer JB, Sirlin CB.J Magn Reson Imaging. 2018 Feb;47(2):418-424. doi: 10.1002/jmri.25748. Epub 2017 May 25.PMID: 28543915 Free PMC article. 

47 Pediatric Psoriasis Comorbidity Screening Guidelines. 

Osier E, Wang AS, Tollefson MM, Cordoro KM, Daniels SR, Eichenfield A, Gelfand JM, Gottlieb AB, Kimball AB, Lebwohl M, Mehta NN, Paller AS, Schwimmer JB, Styne DM, Van Voorhees AS, Tom WL, Eichenfield LF.JAMA Dermatol. 2017 Jul 1;153(7):698-704. doi: 10.1001/jamadermatol.2017.0499.PMID: 28514463 Free PMC article. 

48 Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease. 

Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB.Hepatology. 2017 Nov;66(5):1474-1485. doi: 10.1002/hep.29241. Epub 2017 Oct 9.PMID: 28493388 Free PMC article. 

49 Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children. 

Newton KP, Feldman HS, Chambers CD, Wilson L, Behling C, Clark JM, Molleston JP, Chalasani N, Sanyal AJ, Fishbein MH, Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).J Pediatr. 2017 Aug;187:141-146.e1. doi: 10.1016/j.jpeds.2017.03.007. Epub 2017 Mar 30.PMID: 28366357 Free PMC article. 

50 Accuracy of PDFF estimation by magnitude-based and complex-based MRI in children with MR spectroscopy as a reference. 

Haufe WM, Wolfson T, Hooker CA, Hooker JC, Covarrubias Y, Schlein AN, Hamilton G, Middleton MS, Angeles JE, Hernando D, Reeder SB, Schwimmer JB, Sirlin CB.J Magn Reson Imaging. 2017 Dec;46(6):1641-1647. doi: 10.1002/jmri.25699. Epub 2017 Mar 21.PMID: 28323377 Free PMC article. 

51 In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis. 

Africa JA, Behling CA, Brunt EM, Zhang N, Luo Y, Wells A, Hou J, Belt PH, Kohil R, Lavine JE, Molleston JP, Newton KP, Whitington PF, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network.Clin Gastroenterol Hepatol. 2018 Mar;16(3):438-446.e1. doi: 10.1016/j.cgh.2017.02.030. Epub 2017 Mar 7.PMID: 28286193 Free PMC article. 

52 Race/ethnic and sex disparities in the non-alcoholic fatty liver disease-abdominal aortic calcification association: The Multi-Ethnic Study of Atherosclerosis. 

Remigio-Baker RA, Allison MA, Forbang NI, Loomba R, Anderson CAM, Budoff M, Schwimmer JB, Blumenthal RS, Ouyang P, Criqui MH.Atherosclerosis. 2017 Mar;258:89-96. doi: 10.1016/j.atherosclerosis.2016.11.021. Epub 2016 Nov 17.PMID: 28235711 Free PMC article. 

53 Liver histology and diffusion-weighted MRI in children with nonalcoholic fatty liver disease: A MAGNET study. 

Manning P, Murphy P, Wang K, Hooker J, Wolfson T, Middleton MS, Newton KP, Behling C, Awai HI, Durelle J, Paiz MN, Angeles JE, De La Pena D, McCutchan JA, Schwimmer JB, Sirlin CB.J Magn Reson Imaging. 2017 Oct;46(4):1149-1158. doi: 10.1002/jmri.25663. Epub 2017 Feb 22.PMID: 28225568 Free PMC article. 

54 NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN). 

Vos MB, Abrams SH, Barlow SE, Caprio S, Daniels SR, Kohli R, Mouzaki M, Sathya P, Schwimmer JB, Sundaram SS, Xanthakos SA.J Pediatr Gastroenterol Nutr. 2017 Feb;64(2):319-334. doi: 10.1097/MPG.0000000000001482.PMID: 28107283 Free PMC article. 

55 Bone marrow fat content is correlated with hepatic fat content in paediatric non-alcoholic fatty liver disease. 

Yu NY, Wolfson T, Middleton MS, Hamilton G, Gamst A, Angeles JE, Schwimmer JB, Sirlin CB.Clin Radiol. 2017 May;72(5):425.e9-425.e14. doi: 10.1016/j.crad.2016.11.017. Epub 2017 Jan 5.PMID: 28063601 Free PMC article. 

56 In Children With Nonalcoholic Fatty Liver Disease, Cysteamine Bitartrate Delayed Release Improves Liver Enzymes but Does Not Reduce Disease Activity Scores. 

Schwimmer JB, Lavine JE, Wilson LA, Neuschwander-Tetri BA, Xanthakos SA, Kohli R, Barlow SE, Vos MB, Karpen SJ, Molleston JP, Whitington PF, Rosenthal P, Jain AK, Murray KF, Brunt EM, Kleiner DE, Van Natta ML, Clark JM, Tonascia J, Doo E; NASH CRN.Gastroenterology. 2016 Dec;151(6):1141-1154.e9. doi: 10.1053/j.gastro.2016.08.027. Epub 2016 Aug 26.PMID: 27569726 Free PMC article. Clinical Trial. 

57 Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms. 

Nelson JE, Handa P, Aouizerat B, Wilson L, Vemulakonda LA, Yeh MM, Kowdley KV; NASH Clinical Research Network.Aliment Pharmacol Ther. 2016 Dec;44(11-12):1253-1264. doi: 10.1111/apt.13824. Epub 2016 Oct 11.PMID: 27730688 Free PMC article. 

58 Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. 

Newton KP, Hou J, Crimmins NA, Lavine JE, Barlow SE, Xanthakos SA, Africa J, Behling C, Donithan M, Clark JM, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network.JAMA Pediatr. 2016 Oct 3;170(10):e161971. doi: 10.1001/jamapediatrics.2016.1971. Epub 2016 Oct 3.PMID: 27478956 Free PMC article. 

59 Clinical advances in pediatric nonalcoholic fatty liver disease. 

Schwimmer JB. Hepatology. 2016 May;63(5):1718-25. doi: 10.1002/hep.28441. Epub 2016 Mar 4.PMID: 27100147 Free PMC article. Review. No abstract available. 

60 The Progression and Natural History of Pediatric Nonalcoholic Fatty Liver Disease. 

Goyal NP, Schwimmer JB. Clin Liver Dis. 2016 May;20(2):325-38. doi: 10.1016/j.cld.2015.10.003. Epub 2015 Dec 14.PMID: 27063272 Free PMC article. Review. 

61 Lifestyle Interventions Including Nutrition, Exercise, and Supplements for Nonalcoholic Fatty Liver Disease in Children. 

Africa JA, Newton KP, Schwimmer JB.Dig Dis Sci. 2016 May;61(5):1375-86. doi: 10.1007/s10620-016-4126-1. Epub 2016 Apr 4.PMID: 27041377 Free PMC article. Review. 

62 Comparison of the Phenotype and Approach to Pediatric vs Adult Patients With Nonalcoholic Fatty Liver Disease. 

Nobili V, Alisi A, Newton KP, Schwimmer JB.Gastroenterology. 2016 Jun;150(8):1798-810. doi: 10.1053/j.gastro.2016.03.009. Epub 2016 Mar 19.PMID: 27003600 Free PMC article. Review. 

63 Pediatric Nonalcoholic Fatty Liver Disease: A Report from the Expert Committee on Nonalcoholic Fatty Liver Disease (ECON). 

Kohli R, Sunduram S, Mouzaki M, Ali S, Sathya P, Abrams S, Xanthakos SA, Vos M, Schwimmer JB.J Pediatr. 2016 May;172:9-13. doi: 10.1016/j.jpeds.2015.12.016. Epub 2016 Jan 1.PMID: 26749112 Free PMC article. No abstract available. 

64 Feasibility of and agreement between MR imaging and spectroscopic estimation of hepatic proton density fat fraction in children with known or suspected nonalcoholic fatty liver disease. 

Achmad E, Yokoo T, Hamilton G, Heba ER, Hooker JC, Changchien C, Schroeder M, Wolfson T, Gamst A, Schwimmer JB, Lavine JE, Sirlin CB, Middleton MS.Abdom Imaging. 2015 Oct;40(8):3084-90. doi: 10.1007/s00261-015-0506-9.PMID: 26205992 Free PMC article. 

65 Nonalcoholic Fatty Liver Disease in Latinos. 

Saab S, Manne V, Nieto J, Schwimmer JB, Chalasani NP.Clin Gastroenterol Hepatol. 2016 Jan;14(1):5-12; quiz e9-10. doi: 10.1016/j.cgh.2015.05.001. Epub 2015 May 11.PMID: 25976180 Review. 

66 Paediatric gastroenterology. On a knife-edge--weight-loss surgery for NAFLD in adolescents. 

Xanthakos SA, Schwimmer JB.Nat Rev Gastroenterol Hepatol. 2015 Jun;12(6):316-8. doi: 10.1038/nrgastro.2015.59. Epub 2015 Apr 14.PMID: 25869913 Free PMC article. 

67 Accuracy of multiecho magnitude-based MRI (M-MRI) for estimation of hepatic proton density fat fraction (PDFF) in children. 

Zand KA, Shah A, Heba E, Wolfson T, Hamilton G, Lam J, Chen J, Hooker JC, Gamst AC, Middleton MS, Schwimmer JB, Sirlin CB.J Magn Reson Imaging. 2015 Nov;42(5):1223-32. doi: 10.1002/jmri.24888. Epub 2015 Apr 3.PMID: 25847512 Free PMC article. 

68 Improvement in liver histology is associated with reduction in dyslipidemia in children with nonalcoholic fatty liver disease. 

Corey KE, Vuppalanchi R, Vos M, Kohli R, Molleston JP, Wilson L, Unalp-Arida A, Cummings OW, Lavine JE, Chalasani N; Nonalcoholic Steatohepatitis Clinical Research Network.J Pediatr Gastroenterol Nutr. 2015 Mar;60(3):360-7. doi: 10.1097/MPG.0000000000000584.PMID: 25714579 Free PMC article. Clinical Trial. 

69 Reproducibility of MR-based liver fat quantification across field strength: Same-day comparison between 1.5T and 3T in obese subjects. 

Artz NS, Haufe WM, Hooker CA, Hamilton G, Wolfson T, Campos GM, Gamst AC, Schwimmer JB, Sirlin CB, Reeder SB.J Magn Reson Imaging. 2015 Sep;42(3):811-7. doi: 10.1002/jmri.24842. Epub 2015 Jan 23.PMID: 25620624 Free PMC article. 

70 Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease. 

Schwimmer JB, Middleton MS, Behling C, Newton KP, Awai HI, Paiz MN, Lam J, Hooker JC, Hamilton G, Fontanesi J, Sirlin CB.Hepatology. 2015 Jun;61(6):1887-95. doi: 10.1002/hep.27666. Epub 2015 Feb 5.PMID: 25529941 Free PMC article. Clinical Trial. 

71 Longitudinal assessment of high blood pressure in children with nonalcoholic fatty liver disease. 

Schwimmer JB, Zepeda A, Newton KP, Xanthakos SA, Behling C, Hallinan EK, Donithan M, Tonascia J; Nonalcoholic Steatohepatitis Clinical Research Network.PLoS One. 2014 Nov 24;9(11):e112569. doi: 10.1371/journal.pone.0112569. eCollection 2014.PMID: 25419656 Free PMC article. 

72 On the origin of pediatric nonalcoholic Fatty liver disease. 

Ugalde-Nicalo PA, Schwimmer JB.J Pediatr Gastroenterol Nutr. 2015 Feb;60(2):147-8. doi: 10.1097/MPG.0000000000000618.PMID: 25373858 Free PMC article. No abstract available. 

73 Relationship between changes in serum levels of keratin 18 and changes in liver histology in children and adults with nonalcoholic fatty liver disease. 

Vuppalanchi R, Jain AK, Deppe R, Yates K, Comerford M, Masuoka HC, Neuschwander-Tetri BA, Loomba R, Brunt EM, Kleiner DE, Molleston JP, Schwimmer JB, Lavine JE, Tonascia J, Chalasani N.Clin Gastroenterol Hepatol. 2014 Dec;12(12):2121-30.e1-2. doi: 10.1016/j.cgh.2014.05.010. Epub 2014 May 17.PMID: 24846279 Free PMC article. 

74 Letter: gender-associated cell-free microRNA profiles in non-alcoholic fatty liver disease--authors' reply. 

Newton KP, Awai HI, Feldstein AE, Schwimmer JB.Aliment Pharmacol Ther. 2014 May;39(9):999. doi: 10.1111/apt.12713.PMID: 24689350 Free article. No abstract available. 

75 Histological abnormalities in children with nonalcoholic fatty liver disease and normal or mildly elevated alanine aminotransferase levels. 

Molleston JP, Schwimmer JB, Yates KP, Murray KF, Cummings OW, Lavine JE, Brunt EM, Scheimann AO, Unalp-Arida A; NASH Clinical Research Network.J Pediatr. 2014 Apr;164(4):707-713.e3. doi: 10.1016/j.jpeds.2013.10.071. Epub 2013 Dec 19.PMID: 24360992 Free PMC article. 

76 Paediatric gastroenterology evaluation of overweight and obese children referred from primary care for suspected non-alcoholic fatty liver disease. 

Schwimmer JB, Newton KP, Awai HI, Choi LJ, Garcia MA, Ellis LL, Vanderwall K, Fontanesi J.Aliment Pharmacol Ther. 2013 Nov;38(10):1267-77. doi: 10.1111/apt.12518. Epub 2013 Oct 1.PMID: 24117728 Free PMC article. 

77 Evidence and recommendations for imaging liver fat in children, based on systematic review. 

Awai HI, Newton KP, Sirlin CB, Behling C, Schwimmer JB.Clin Gastroenterol Hepatol. 2014 May;12(5):765-73. doi: 10.1016/j.cgh.2013.09.050. Epub 2013 Sep 30.PMID: 24090729 Free PMC article. Review. 

78 Vitamin E and changes in serum alanine aminotransferase levels in patients with non-alcoholic steatohepatitis. 

Hoofnagle JH, Van Natta ML, Kleiner DE, Clark JM, Kowdley KV, Loomba R, Neuschwander-Tetri BA, Sanyal AJ, Tonascia J; Non-alcoholic Steatohepatitis Clinical Research Network (NASH CRN).Aliment Pharmacol Ther. 2013 Jul;38(2):134-43. doi: 10.1111/apt.12352. Epub 2013 May 29.PMID: 23718573 Free PMC article. Clinical Trial. 

79 Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. 

Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin CB.J Magn Reson Imaging. 2014 Feb;39(2):440-7. doi: 10.1002/jmri.24153. Epub 2013 Apr 17.PMID: 23596052 Free PMC article. 

80 Liver toxicity of anabolic androgenic steroid use in an adolescent with nonalcoholic fatty liver disease. 

Awai HI, Yu EL, Ellis LS, Schwimmer JB.J Pediatr Gastroenterol Nutr. 2014 Sep;59(3):e32-3. doi: 10.1097/MPG.0b013e3182952e74.PMID: 23568051 Free PMC article. 

81 Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. 

Tang A, Tan J, Sun M, Hamilton G, Bydder M, Wolfson T, Gamst AC, Middleton M, Brunt EM, Loomba R, Lavine JE, Schwimmer JB, Sirlin CB.Radiology. 2013 May;267(2):422-31. doi: 10.1148/radiol.12120896. Epub 2013 Feb 4.PMID: 23382291 Free PMC article. 

82 Clinical trials for adolescent obesity: cooking up an alphabet stew of what to do. 

Schwimmer JB.JAMA Pediatr. 2013 Apr;167(4):391-3. doi: 10.1001/jamapediatrics.2013.1661.PMID: 23381196 No abstract available. 

83 Hedgehog pathway and pediatric nonalcoholic fatty liver disease. 

Swiderska-Syn M, Suzuki A, Guy CD, Schwimmer JB, Abdelmalek MF, Lavine JE, Diehl AM.Hepatology. 2013 May;57(5):1814-25. doi: 10.1002/hep.26230. Epub 2013 Apr 1.PMID: 23300059 Free PMC article. 

84 Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations. 

Nelson JE, Brunt EM, Kowdley KV; Nonalcoholic Steatohepatitis Clinical Research Network.Hepatology. 2012 Nov;56(5):1730-40. doi: 10.1002/hep.25856. Epub 2012 Sep 20.PMID: 22611049 Free PMC article. 

85 Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease (NAFLD). 

Dunn W, Sanyal AJ, Brunt EM, Unalp-Arida A, Donohue M, McCullough AJ, Schwimmer JB.J Hepatol. 2012 Aug;57(2):384-91. doi: 10.1016/j.jhep.2012.03.024. Epub 2012 Apr 17.PMID: 22521357 Free PMC article. 

86 Association between puberty and features of nonalcoholic fatty liver disease. 

Suzuki A, Abdelmalek MF, Schwimmer JB, Lavine JE, Scheimann AO, Unalp-Arida A, Yates KP, Sanyal AJ, Guy CD, Diehl AM; Nonalcoholic Steatohepatitis Clinical Research Network.Clin Gastroenterol Hepatol. 2012 Jul;10(7):786-94. doi: 10.1016/j.cgh.2012.01.020. Epub 2012 Feb 14.PMID: 22343513 Free PMC article. 

87 Choline intake in a large cohort of patients with nonalcoholic fatty liver disease. 

Guerrerio AL, Colvin RM, Schwartz AK, Molleston JP, Murray KF, Diehl A, Mohan P, Schwimmer JB, Lavine JE, Torbenson MS, Scheimann AO.Am J Clin Nutr. 2012 Apr;95(4):892-900. doi: 10.3945/ajcn.111.020156. Epub 2012 Feb 15.PMID: 22338037 Free PMC article. Clinical Trial. 

88 Hedgehog pathway activation parallels histologic severity of injury and fibrosis in human nonalcoholic fatty liver disease. 

Guy CD, Suzuki A, Zdanowicz M, Abdelmalek MF, Burchette J, Unalp A, Diehl AM; NASH CRN.Hepatology. 2012 Jun;55(6):1711-21. doi: 10.1002/hep.25559. Epub 2012 Apr 18.PMID: 22213086 Free PMC article. 

89 Correlation of vitamin E, uric acid, and diet composition with histologic features of pediatric NAFLD. 

Vos MB, Colvin R, Belt P, Molleston JP, Murray KF, Rosenthal P, Schwimmer JB, Tonascia J, Unalp A, Lavine JE; NASH CRN Research Group.J Pediatr Gastroenterol Nutr. 2012 Jan;54(1):90-6. doi: 10.1097/MPG.0b013e318229da1a.PMID: 22197855 Free PMC article. 

90 Non-alcoholic fatty liver disease is associated with low bone mineral density in obese children. 

Pardee PE, Dunn W, Schwimmer JB.Aliment Pharmacol Ther. 2012 Jan;35(2):248-54. doi: 10.1111/j.1365-2036.2011.04924.x. Epub 2011 Nov 24.PMID: 22111971 Free PMC article. 

91 Effect of vitamin E or metformin for treatment of nonalcoholic fatty liver disease in children and adolescents: the TONIC randomized controlled trial. 

Lavine JE, Schwimmer JB, Van Natta ML, Molleston JP, Murray KF, Rosenthal P, Abrams SH, Scheimann AO, Sanyal AJ, Chalasani N, Tonascia J, Ünalp A, Clark JM, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR; Nonalcoholic Steatohepatitis Clinical Research Network.JAMA. 2011 Apr 27;305(16):1659-68. doi: 10.1001/jama.2011.520.PMID: 21521847 Free PMC article. Clinical Trial. 

92 Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. 

Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS; NASH CRN; GIANT Consortium; MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB; GOLD Consortium.PLoS Genet. 2011 Mar;7(3):e1001324. doi: 10.1371/journal.pgen.1001324. Epub 2011 Mar 10.PMID: 21423719 Free PMC article. 

93 Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease. 

Dohil R, Schmeltzer S, Cabrera BL, Wang T, Durelle J, Duke KB, Schwimmer JB, Lavine JE.Aliment Pharmacol Ther. 2011 May;33(9):1036-44. doi: 10.1111/j.1365-2036.2011.04626.x. Epub 2011 Mar 13.PMID: 21395631 Free article. 

94 Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings. 

Brunt EM, Kleiner DE, Wilson LA, Belt P, Neuschwander-Tetri BA; NASH Clinical Research Network (CRN).Hepatology. 2011 Mar;53(3):810-20. doi: 10.1002/hep.24127. Epub 2011 Feb 11.PMID: 21319198 Free PMC article. 

95 Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease. 

Barshop NJ, Capparelli EV, Sirlin CB, Schwimmer JB, Lavine JE.J Pediatr Gastroenterol Nutr. 2011 Feb;52(2):198-202. doi: 10.1097/MPG.0b013e3181f9b3a0.PMID: 21240014 Free PMC article. 

96 Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T. 

Yokoo T, Shiehmorteza M, Hamilton G, Wolfson T, Schroeder ME, Middleton MS, Bydder M, Gamst AC, Kono Y, Kuo A, Patton HM, Horgan S, Lavine JE, Schwimmer JB, Sirlin CB.Radiology. 2011 Mar;258(3):749-59. doi: 10.1148/radiol.10100659. Epub 2011 Jan 6.PMID: 21212366 Free PMC article. 

97 Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. 

Kistler KD, Brunt EM, Clark JM, Diehl AM, Sallis JF, Schwimmer JB; NASH CRN Research Group.Am J Gastroenterol. 2011 Mar;106(3):460-8; quiz 469. doi: 10.1038/ajg.2010.488. Epub 2011 Jan 4.PMID: 21206486 Free PMC article. 

98 Pediatric nonalcoholic fatty liver disease: a comprehensive review. 

Lindbäck SM, Gabbert C, Johnson BL, Smorodinsky E, Sirlin CB, Garcia N, Pardee PE, Kistler KD, Schwimmer JB.Adv Pediatr. 2010;57(1):85-140. doi: 10.1016/j.yapd.2010.08.006.PMID: 21056736 Review. No abstract available. 

99 Adenovirus 36 and obesity in children and adolescents. 

Gabbert C, Donohue M, Arnold J, Schwimmer JB.Pediatrics. 2010 Oct;126(4):721-6. doi: 10.1542/peds.2009-3362. Epub 2010 Sep 20.PMID: 20855385 

100Clinical, laboratory and histological associations in adults with nonalcoholic fatty liver disease. 

Neuschwander-Tetri BA, Clark JM, Bass NM, Van Natta ML, Unalp-Arida A, Tonascia J, Zein CO, Brunt EM, Kleiner DE, McCullough AJ, Sanyal AJ, Diehl AM, Lavine JE, Chalasani N, Kowdley KV; NASH Clinical Research Network.Hepatology. 2010 Sep;52(3):913-24. doi: 10.1002/hep.23784.PMID: 20648476 Free PMC article. 

101 Nonalcoholic fatty liver disease as a comorbidity of childhood obesity. 

Barshop NJ, Francis CS, Schwimmer JB, Lavine JE.Ped Health. 2009 Jun 1;3(3):271-281. doi: 10.2217/phe.09.21.PMID: 20556232 Free PMC article. 

102 Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. 

Sanyal AJ, Chalasani N, Kowdley KV, McCullough A, Diehl AM, Bass NM, Neuschwander-Tetri BA, Lavine JE, Tonascia J, Unalp A, Van Natta M, Clark J, Brunt EM, Kleiner DE, Hoofnagle JH, Robuck PR; NASH CRN.N Engl J Med. 2010 May 6;362(18):1675-85. doi: 10.1056/NEJMoa0907929. Epub 2010 Apr 28.PMID: 20427778 Free PMC article. Clinical Trial. 

103 Association between metabolic syndrome and liver histology among children with nonalcoholic Fatty liver disease. 

Patton HM, Yates K, Unalp-Arida A, Behling CA, Huang TT, Rosenthal P, Sanyal AJ, Schwimmer JB, Lavine JE.Am J Gastroenterol. 2010 Sep;105(9):2093-102. doi: 10.1038/ajg.2010.152. Epub 2010 Apr 6.PMID: 20372110 Free PMC article. 

104 Increased fructose consumption is associated with fibrosis severity in patients with nonalcoholic fatty liver disease. 

Abdelmalek MF, Suzuki A, Guy C, Unalp-Arida A, Colvin R, Johnson RJ, Diehl AM; Nonalcoholic Steatohepatitis Clinical Research Network.Hepatology. 2010 Jun;51(6):1961-71. doi: 10.1002/hep.23535.PMID: 20301112 Free PMC article. 

105 SAFETY study: alanine aminotransferase cutoff values are set too high for reliable detection of pediatric chronic liver disease. 

Schwimmer JB, Dunn W, Norman GJ, Pardee PE, Middleton MS, Kerkar N, Sirlin CB.Gastroenterology. 2010 Apr;138(4):1357-64, 1364.e1-2. doi: 10.1053/j.gastro.2009.12.052. Epub 2010 Jan 11.PMID: 20064512 Free PMC article. 

106 Symptoms and quality of life in obese children and adolescents with non-alcoholic fatty liver disease. 

Kistler KD, Molleston J, Unalp A, Abrams SH, Behling C, Schwimmer JB; Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN).Aliment Pharmacol Ther. 2010 Feb 1;31(3):396-406. doi: 10.1111/j.1365-2036.2009.04181.x. Epub 2009 Oct 23.PMID: 19863497 Free PMC article. 

107 Treatment of nonalcoholic fatty liver disease in children: TONIC trial design. 

Lavine JE, Schwimmer JB, Molleston JP, Scheimann AO, Murray KF, Abrams SH, Rosenthal P, Sanyal AJ, Robuck PR, Brunt EM, Unalp A, Tonascia J; Nonalcoholic Steatohepatitis Clinical Research Network Research Group.Contemp Clin Trials. 2010 Jan;31(1):62-70. doi: 10.1016/j.cct.2009.09.001. Epub 2009 Sep 15.PMID: 19761871 Free PMC article. Clinical Trial. 

108 Advances in pediatric nonalcoholic fatty liver disease. 

Loomba R, Sirlin CB, Schwimmer JB, Lavine JE.Hepatology. 2009 Oct;50(4):1282-93. doi: 10.1002/hep.23119.PMID: 19637286 Free PMC article. Review. 

109 Diagnosis and treatment of pediatric nonalcoholic steatohepatitis and the implications for bariatric surgery. 

Pardee PE, Lavine JE, Schwimmer JB.Semin Pediatr Surg. 2009 Aug;18(3):144-51. doi: 10.1053/j.sempedsurg.2009.04.004.PMID: 19573756 Free PMC article. 

110 Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification. 

Hamilton G, Middleton MS, Bydder M, Yokoo T, Schwimmer JB, Kono Y, Patton HM, Lavine JE, Sirlin CB.J Magn Reson Imaging. 2009 Jul;30(1):145-52. doi: 10.1002/jmri.21809.PMID: 19557733 Free PMC article. Clinical Trial. 

111 Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. 

Shah AG, Lydecker A, Murray K, Tetri BN, Contos MJ, Sanyal AJ; Nash Clinical Research Network.Clin Gastroenterol Hepatol. 2009 Oct;7(10):1104-12. doi: 10.1016/j.cgh.2009.05.033. Epub 2009 Jun 10.PMID: 19523535 Free PMC article. 

112 Quality of life in adults with nonalcoholic fatty liver disease: baseline data from the nonalcoholic steatohepatitis clinical research network. 

David K, Kowdley KV, Unalp A, Kanwal F, Brunt EM, Schwimmer JB; NASH CRN Research Group.Hepatology. 2009 Jun;49(6):1904-12. doi: 10.1002/hep.22868.PMID: 19434741 Free PMC article. 

113 Influence of race, ethnicity, and culture on childhood obesity: implications for prevention and treatment. 

Caprio S, Daniels SR, Drewnowski A, Kaufman FR, Palinkas LA, Rosenbloom AL, Schwimmer JB.Obesity (Silver Spring). 2008 Dec;16(12):2566-77. doi: 10.1038/oby.2008.398.PMID: 19279654 Free article. No abstract available. 

114 Nonalcoholic fatty liver disease: diagnostic and fat-grading accuracy of low-flip-angle multiecho gradient-recalled-echo MR imaging at 1.5 T. 

Yokoo T, Bydder M, Hamilton G, Middleton MS, Gamst AC, Wolfson T, Hassanein T, Patton HM, Lavine JE, Schwimmer JB, Sirlin CB.Radiology. 2009 Apr;251(1):67-76. doi: 10.1148/radiol.2511080666. Epub 2009 Feb 12.PMID: 19221054 Free PMC article. 

115 Heritability of nonalcoholic fatty liver disease. 

Schwimmer JB, Celedon MA, Lavine JE, Salem R, Campbell N, Schork NJ, Shiehmorteza M, Yokoo T, Chavez A, Middleton MS, Sirlin CB.Gastroenterology. 2009 May;136(5):1585-92. doi: 10.1053/j.gastro.2009.01.050. Epub 2009 Jan 25.PMID: 19208353 Free PMC article. 

116 Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis. 

Cassidy FH, Yokoo T, Aganovic L, Hanna RF, Bydder M, Middleton MS, Hamilton G, Chavez AD, Schwimmer JB, Sirlin CB.Radiographics. 2009 Jan-Feb;29(1):231-60. doi: 10.1148/rg.291075123.PMID: 19168847 

117 Clinical correlates of histopathology in pediatric nonalcoholic steatohepatitis. 

Patton HM, Lavine JE, Van Natta ML, Schwimmer JB, Kleiner D, Molleston J; Nonalcoholic Steatohepatitis Clinical Research Network.Gastroenterology. 2008 Dec;135(6):1961-1971.e2. doi: 10.1053/j.gastro.2008.08.050. Epub 2008 Sep 3.PMID: 19013463 Free PMC article. Clinical Trial. 

118 Hepatic, cardiovascular, and endocrine outcomes of the histological subphenotypes of nonalcoholic fatty liver disease. 

Rubinstein E, Lavine JE, Schwimmer JB.Semin Liver Dis. 2008 Nov;28(4):380-5. doi: 10.1055/s-0028-1091982. Epub 2008 Oct 27.PMID: 18956294 Review. 

119 Influence of race, ethnicity, and culture on childhood obesity: implications for prevention and treatment: a consensus statement of Shaping America's Health and the Obesity Society. 

Caprio S, Daniels SR, Drewnowski A, Kaufman FR, Palinkas LA, Rosenbloom AL, Schwimmer JB.Diabetes Care. 2008 Nov;31(11):2211-21. doi: 10.2337/dc08-9024.PMID: 18955718 Free PMC article. Review. No abstract available. 

120 Suspected nonalcoholic fatty liver disease and mortality risk in a population-based cohort study. 

Dunn W, Xu R, Wingard DL, Rogers C, Angulo P, Younossi ZM, Schwimmer JB.Am J Gastroenterol. 2008 Sep;103(9):2263-71. doi: 10.1111/j.1572-0241.2008.02034.x. Epub 2008 Aug 5.PMID: 18684196 Free PMC article. 

121 Fast break on the fat brake: mechanism of peroxisome proliferator-activated receptor-delta regulation of lipid accumulation in hepatocytes. 

Andrews DB, Schwimmer JB, Lavine JE.Hepatology. 2008 Aug;48(2):355-7. doi: 10.1002/hep.22505.PMID: 18666254 No abstract available. 

122 Cardiovascular risk factors and the metabolic syndrome in pediatric nonalcoholic fatty liver disease. 

Schwimmer JB, Pardee PE, Lavine JE, Blumkin AK, Cook S.Circulation. 2008 Jul 15;118(3):277-83. doi: 10.1161/CIRCULATIONAHA.107.739920. Epub 2008 Jun 30.PMID: 18591439 Free PMC article. 

123 Modest wine drinking and decreased prevalence of suspected nonalcoholic fatty liver disease. 

Dunn W, Xu R, Schwimmer JB.Hepatology. 2008 Jun;47(6):1947-54. doi: 10.1002/hep.22292.PMID: 18454505 Free PMC article. 

124 The obesity epidemic and nonalcoholic fatty liver disease in children. 

Dunn W, Schwimmer JB.Curr Gastroenterol Rep. 2008 Feb;10(1):67-72. doi: 10.1007/s11894-008-0011-1.PMID: 18417045 Review. 

125 Review article: epidemiology, pathogenesis and potential treatments of paediatric non-alcoholic fatty liver disease. 

Barshop NJ, Sirlin CB, Schwimmer JB, Lavine JE.Aliment Pharmacol Ther. 2008 Jul;28(1):13-24. doi: 10.1111/j.1365-2036.2008.03703.x. Epub 2008 Apr 4.PMID: 18397387 Free article. Review. 

126 Musculoskeletal pain in obese children and adolescents. 

Stovitz SD, Pardee PE, Vazquez G, Duval S, Schwimmer JB.Acta Paediatr. 2008 Apr;97(4):489-93. doi: 10.1111/j.1651-2227.2008.00724.x.PMID: 18363957 

127 Pediatric obesity: the unique issues in Latino-American male youth. 

Stovitz SD, Schwimmer JB, Martinez H, Story MT.Am J Prev Med. 2008 Feb;34(2):153-60. doi: 10.1016/j.amepre.2007.09.034.PMID: 18201646 

128 Relaxation effects in the quantification of fat using gradient echo imaging. 

Bydder M, Yokoo T, Hamilton G, Middleton MS, Chavez AD, Schwimmer JB, Lavine JE, Sirlin CB.Magn Reson Imaging. 2008 Apr;26(3):347-59. doi: 10.1016/j.mri.2007.08.012. Epub 2008 Feb 21.PMID: 18093781 Free PMC article. 

129 Television viewing and hypertension in obese children. 

Pardee PE, Norman GJ, Lustig RH, Preud'homme D, Schwimmer JB.Am J Prev Med. 2007 Dec;33(6):439-43. doi: 10.1016/j.amepre.2007.07.036.PMID: 18022058 

130 Definitive diagnosis and assessment of risk for nonalcoholic fatty liver disease in children and adolescents. 

Schwimmer JB.Semin Liver Dis. 2007 Aug;27(3):312-8. doi: 10.1055/s-2007-985075.PMID: 17682977 Review.

131 Health-related quality of life in pediatric patients with irritable bowel syndrome: a comparative analysis. 

Varni JW, Lane MM, Burwinkle TM, Fontaine EN, Youssef NN, Schwimmer JB, Pardee PE, Pohl JF, Easley DJ.J Dev Behav Pediatr. 2006 Dec;27(6):451-8. doi: 10.1097/00004703-200612000-00001.PMID: 17164617 

132 Pediatric nonalcoholic fatty liver disease: a critical appraisal of current data and implications for future research. 

Patton HM, Sirlin C, Behling C, Middleton M, Schwimmer JB, Lavine JE.J Pediatr Gastroenterol Nutr. 2006 Oct;43(4):413-27. doi: 10.1097/01.mpg.0000239995.58388.56.PMID: 17033514 Review. 

133 Prevalence of fatty liver in children and adolescents. 

Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C.Pediatrics. 2006 Oct;118(4):1388-93. doi: 10.1542/peds.2006-1212.PMID: 17015527 

134 Clinical Research Network launches TONIC trial for treatment of nonalcoholic fatty liver disease in children. 

Lavine JE, Schwimmer JB.J Pediatr Gastroenterol Nutr. 2006 Feb;42(2):129-30. doi: 10.1097/01.mpg.0000189332.77644.1f.PMID: 16456401 No abstract available. 

135 Histopathology of pediatric nonalcoholic fatty liver disease. 

Schwimmer JB, Behling C, Newbury R, Deutsch R, Nievergelt C, Schork NJ, Lavine JE.Hepatology. 2005 Sep;42(3):641-9. doi: 10.1002/hep.20842.PMID: 16116629 

136 Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study. 

Xanthakos SA, Schwimmer JB, Melin-Aldana H, Rothenberg ME, Witte DP, Cohen MB.J Pediatr Gastroenterol Nutr. 2005 Jul;41(1):16-22. doi: 10.1097/01.mpg.0000161039.96200.f1.PMID: 15990624 

137 Influence of gender, race, and ethnicity on suspected fatty liver in obese adolescents. 

Schwimmer JB, McGreal N, Deutsch R, Finegold MJ, Lavine JE.Pediatrics. 2005 May;115(5):e561-5. doi: 10.1542/peds.2004-1832.PMID: 15867021 

138 A phase 2 clinical trial of metformin as a treatment for non-diabetic paediatric non-alcoholic steatohepatitis. 

Schwimmer JB, Middleton MS, Deutsch R, Lavine JE. Aliment Pharmacol Ther. 2005 Apr 1;21(7):871-9. doi: 10.1111/j.1365-2036.2005.02420.x.PMID: 15801922 Free article. Clinical Trial. 

139 Abnormal aminotransferase activity in women with polycystic ovary syndrome. 

Schwimmer JB, Khorram O, Chiu V, Schwimmer WB. Fertil Steril. 2005 Feb;83(2):494-7. doi: 10.1016/j.fertnstert.2004.08.020.PMID: 15705403 

140 Nonalcoholic fatty liver disease in the pediatric population. 

Lavine JE, Schwimmer JB. Clin Liver Dis. 2004 Aug;8(3):549-58, viii-ix. doi: 10.1016/j.cld.2004.04.010.PMID: 15331063 Review.

141 Managing overweight in older children and adolescents. 

Schwimmer JB.Pediatr Ann. 2004 Jan;33(1):39-44. doi: 10.3928/0090-4481-20040101-11.PMID: 14981868 Review. 

142 Lumen and the liver--together again in NASHville. 

Schwimmer JB, Lavine JE.J Pediatr Gastroenterol Nutr. 2003 Oct;37(4):523-4. doi: 10.1097/00005176-200310000-00024.PMID: 14579849 No abstract available. 

143 Obesity, insulin resistance, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease. 

Schwimmer JB, Deutsch R, Rauch JB, Behling C, Newbury R, Lavine JE. J Pediatr. 2003 Oct;143(4):500-5. doi: 10.1067/S0022-3476(03)00325-1.PMID: 14571229 

144 Pediatric initiatives within the Nonalcoholic Steatohepatitis-Clinical Research Network (NASH CNR). 

Lavine JE, Schwimmer JB; Nonalcoholic Steatohepatitis-Clinical Research Network. J Pediatr Gastroenterol Nutr. 2003 Sep;37(3):220-1. doi: 10.1097/00005176-200309000-00002.PMID: 12971361 No abstract available. 

145 Health-related quality of life of severely obese children and adolescents. 

Schwimmer JB, Burwinkle TM, Varni JW.JAMA. 2003 Apr 9;289(14):1813-9. doi: 10.1001/jama.289.14.1813.PMID: 12684360 

146 Glutamine promotes triglyceride absorption in a dose-dependent manner. 

Schwimmer JB, Ee L, Zheng S, Tso P. Am J Physiol Gastrointest Liver Physiol. 2002 Feb;282(2):G317-23. doi: 10.1152/ajpgi.2002.282.2.G317.PMID: 11804853 Free article. 

147 Transmission, natural history, and treatment of hepatitis C virus infection in the pediatric population. 

Schwimmer JB, Balistreri WF. Semin Liver Dis. 2000;20(1):37-46. doi: 10.1055/s-2000-9257.PMID: 10895430 Review.