Representative Publications:

mammary stem cell outgrowth

Sun Q, Lesperance J, Wettersten H, Luterstein E, DeRose YS, Welm A, Cheresh DA, Desgrosellier JS. Pro-apoptotic PUMA targets stem-like breast cancer cells to suppress metastasis. J Clin Invest. 2018; 128(1):531-544. *Featured Article PubMed link

Seguin L, Desgrosellier JS, Weis SM, Cheresh DA. Integrins and cancer: regulators of cancer stemness, metastasis, and drug resistance. Trends Cell Biol. 2015; 25(4):234-40. PubMed link

Desgrosellier JS, Lesperance J, Seguin L, Gozo M, Kato S, Franovic A, Yebra M, Shattil SJ, Cheresh DA. Integrin αvβ3 drives Slug activation and stemness in the pregnant and neoplastic mammary gland. Dev Cell. 2014; 30(3):295-308. *Featured Article & Cover PubMed link

Desgrosellier JS, Cheresh DA. Integrins in cancer: Biological implications and therapeutic opportunities. Nat Rev Cancer. 2010; 10(1):9-22. PubMed link

Desgrosellier JS, Barnes LA, Shields DJ, Huang M, Lau SK, Prévost N, Tarin D, Shattil SJ, Cheresh DA. An integrin αvβ3-c-Src oncogenic unit promotes anchorage-independence and tumor progression. Nat Med. 2009; 15(10):1163-1169. PubMed link

For a complete list of Desgrosellier Lab publications click here Publication List.