​Selected Publications by Dr. Ferguson:

1.    Ferguson CJ, Urso OU, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Wu DY, Strauss KA, Jinks RN, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A. APC7 Mediates Ubiquitin Signaling in Constitutive Heterochromatin of the Developing Mammalian Brain. Molecular Cell (revised and resubmitted).

2.    Reddy NC, Majidi SP, Kong L, Nemera M, Ferguson CJ, Moore M, Goncalves TM, Liu HK, Fitzpatrick JA, Zhao G, Yamada T, Bonni A, Gabel HW. CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum. Nature Communications. Volume 12, Article number: 5702 (2021).

3.    Binder ZA, Thorne AH, Bakas S, Wileyto EP, Bilello M, Akbari H, Rathore S, Ha SM, Zhang L, Ferguson CJ, Dahiya S, Bi WL, Reardon DA, Idbaih A, Felsberg J, Hentschel B, Weller M, Bagley SJ, Morrissette JJD, Nasrallah MP, Ma J, Zanca C, Scott AM, Orellana L, Davatzikos C, Furnari FB, O'Rourke DM. Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development. Cancer Cell. 2018 Jul 9;34(1):163-177.e7.

4.    Johanns TM, Ferguson CJ, Grierson PM, Dahiya S, Ansstas G. Rapid Clinical and Radiographic Response with Combined Dabrafenib and Trametinib in Adults With BRAF-Mutated High-Grade Glioma. J. Natl. Compr. Canc. Netw. 2018 Jan; 16(1): 4–10.

5.    Johanns TM, Miller CA, Dorward IG, Tsien C, Chang E, Perry A, Uppaluri R, Ferguson CJ, Schmidt RE, Dahiya S, Ansstas G, Mardis ER, Dunn GP. Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy. Cancer Discovery. 2016 Nov;6(11):1230-1236.

6.    Zhang Y, McCartney AJ, Zolov SN, Ferguson CJ, Meisler MJ, Sutton MJ, Weisman LS.  
Modulation of Synaptic Function by VAC14, a Protein that Regulates the Phosphoinositide PI(3,5)P2EMBO Journal.  2012 Aug 15;31(16):3442-56.

7.    Ferguson CJ*, Lenk GM*, Jones JM, Grant AE, Winters JJ, Dowling JJ, Giger RJ, Meisler MH. Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. Human Molecular Genetics.  2012 Aug 15;21(16):3525-34.

8.    Winters JJ*, Ferguson CJ*, Lenk GM, Giger-Mateeva VI, Shrager P, Meisler MH, Giger RJ.  
Congenital CNS Hypomyelination in the Fig4 Null Mouse Is Rescued by Neuronal Expression of the PI(3,5)P2 Phosphatase Fig4. Journal of Neuroscience.  2011 Nov 30;31(48):17736-51.

9.    Nicholson G, Lenk GM, Reddel SW, Grant AE, Towne CF, Ferguson CJ, Simpson E, Scheuerle A, Yasick M, Hoffman S, Blouin R, Brandt C, Coppola G, Biesecker LG, Batish SD, Meisler MH. Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P2 phosphatase FIG4. Brain.  2011 Jul;134(Pt 7):1959-71.

10.  Lenk GM, Ferguson CJ, Chow CY, Jin N, Jones JM, Grant AE, Zolov SN, Winters JJ, Giger RJ, Dowling JJ, Weisman LS, Meisler MH. Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J. PLoS Genet.  2011 Jun;7(6):e1002104. 

11.  Ferguson CJ, Lenk GM, Meisler MH. PtdIns(3,5)P2 and autophagy in mouse models of neurodegeneration. Autophagy.  2010 Jan 1; 6:1,1-2.

12.  Ferguson CJ, Lenk GM, Meisler MH. Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2Human Molecular Genetics.  2009 Dec 15;18(24):4868-78.

13.  Ferguson C, Larochelle A, Dunbar CE. Hematopoietic stem cell gene therapy: dead or alive? Trends in Biotechnology.  2005 Dec;23(12):589-97.

14.  Calmels B, Ferguson C, Laukkanen MO, Adler R, Faulhaber M, Kim HJ, Sellers S, Hematti P, Schmidt M, von Kalle C, Akagi K, Donahue RE, Dunbar CE. Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells. Blood.  2005 Oct 1;106(7):2530-3. 

15.  Hematti P*, Hong BK*, Ferguson C*, Adler R, Hanawa H, Sellers S, Holt IE, Eckfeldt CE, Sharma Y, Schmidt M, von Kalle C, Persons DA, Billings EM, Verfaillie CM, Nienhuis AW, Wolfsberg TG, Dunbar CE, Calmels B. Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells. PLoS Biology.  2004 Dec;2(12):e423.